OSOPIA® – Synthetic Graft Material with 3DI Surface Technology

OSOPIA® – Synthetic Graft Material with 3DI Surface Technology

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OSOPIA® is a synthetic Biphasic Calcium Phosphate (BCP) manufactured using an innovative proprietary process with 3DI Surface Technology.


Slow resorption profile providing continuous remodeling process for 100% vital bone.


Synthetic graft concept designed for maximum product safety and performance.



OsOpia is a bone grafting material indicated for use in the specific
treatment of extraction sockets and maxillary sinus augmentation procedures.


Miron RJ,Sculean A, Shuang Y,Bosshardt DD, Gruber R, Buser D, Chandad F,Zhang Y. Osteoinductive potential of a novel biphasic calcium phosphate bone graft in comparison with autographs, xenografts, and DFDBA. Clin Oral Implants Res. 2016 Jun;27(6):668-75. doi: 10.1111/clr.12647. (IF = 3.624)

Miron RJ, Shuang Y, Bosshardt DD, Caballé-Serrano J, Chandad F, Zhang Y. Osteogenic gene array of osteoblasts cultured on a novel osteoinductive biphasic calcium phosphate bone grafting material. Clin Oral Investig. 2017 Apr;21(3):801-808. doi: 10.1007/s00784-016-1825-0. Epub 2016 Apr 23. (IF = 2.308)

Miron RJ, Zhang Q, Sculean A, Buser D, Pippenger BE, Dard M, Shirakata Y, Chandad F, Zhang Y. Osteoinductive potential of 4 commonly employed bone grafts. Clin Oral Investig. 2016 Nov;20(8):2259-2265. (IF = 2.308)

Zhang Y, Shuang Y, Zhou W, Fu H, Qian L, Miron RJ. Addition of a synthetically fabricated osteoinductive biphasic calcium phosphate bone graft to BMP2 improves new bone formation. Clin Implant Dent Relat Res. 2016 Dec;18(6):1238-1247. doi: 10.1111/cid.12384. Epub 2015 Oct 28. (IF = 2.939)

Miron RJ, Zhang Y. The Arrival of Synthetic Bone Grafts with Osteoinductive Potential. J J Dent Res. 2014, 1(1): 002.


Barroso-Panella A, Gargallo-Albiol J, Hérnandez-Alfaro FEvaluation of Bone Stability and Esthetic Results After Immediate Implant Placement Using a Novel Synthetic Bone Substitute in the Anterior Zone: Results After 12 Months. Int J Periodontics Restorative Dent. 2018 Mar/Apr;38(2):235-243. doi: 10.11607/prd.2863.