OSOPIA® – Synthetic Graft Material with 3DI Surface Technology

OSOPIA® – Synthetic Graft Material with 3DI Surface Technology

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Description

OSOPIA® is a synthetic Biphasic Calcium Phosphate (BCP) manufactured using an innovative proprietary process that creates a unique active surface on the graft. It is mineralized like FDBA and has a unique 3DI surface that closely mimics the properties of DFDBA. Therefore it resembles a mix of FDBA and DFDBA without the problematic safety and ethical issues of using allograft bone.

OSOPIA BENEFITS:
SUSTAINED REGENERATION

Slow resorption profile providing continuous remodeling process for 100% vital bone. Resorption times closely mimics traditional allograft time frames and can be used in similar indications.

UNIQUE SURFACE TECHNOLOGY

3DI (three-dimensional integrated) microarchitecture is an excellent surface for osteoblast activity. Osopia’s unique micropore size between 0.3 and 1.1 microns results in better bone formation in extraction sockets or sinuses.

SAFE & SUSTAINALBE

Synthetic graft concept designed for maximum product safety and performance. Socially conscious raw materials and no risk of disease transmission.

INDICATIONS:

OSOPIA can be used in following indications:

  • Sinus lift
  • Filling of alveolar defects after tooth extraction (for ridge preservation or delayed implant placement >6 months)

Research

Miron RJ,Sculean A, Shuang Y,Bosshardt DD, Gruber R, Buser D, Chandad F,Zhang Y. Osteoinductive potential of a novel biphasic calcium phosphate bone graft in comparison with autographs, xenografts, and DFDBA. Clin Oral Implants Res. 2016 Jun;27(6):668-75. doi: 10.1111/clr.12647. (IF = 3.624)

Miron RJ, Shuang Y, Bosshardt DD, Caballé-Serrano J, Chandad F, Zhang Y. Osteogenic gene array of osteoblasts cultured on a novel osteoinductive biphasic calcium phosphate bone grafting material. Clin Oral Investig. 2017 Apr;21(3):801-808. doi: 10.1007/s00784-016-1825-0. Epub 2016 Apr 23. (IF = 2.308)

Miron RJ, Zhang Q, Sculean A, Buser D, Pippenger BE, Dard M, Shirakata Y, Chandad F, Zhang Y. Osteoinductive potential of 4 commonly employed bone grafts. Clin Oral Investig. 2016 Nov;20(8):2259-2265. (IF = 2.308)

Zhang Y, Shuang Y, Zhou W, Fu H, Qian L, Miron RJ. Addition of a synthetically fabricated osteoinductive biphasic calcium phosphate bone graft to BMP2 improves new bone formation. Clin Implant Dent Relat Res. 2016 Dec;18(6):1238-1247. doi: 10.1111/cid.12384. Epub 2015 Oct 28. (IF = 2.939)

Miron RJ, Zhang Y. The Arrival of Synthetic Bone Grafts with Osteoinductive Potential. J J Dent Res. 2014, 1(1): 002.

 

Barroso-Panella A, Gargallo-Albiol J, Hérnandez-Alfaro FEvaluation of Bone Stability and Esthetic Results After Immediate Implant Placement Using a Novel Synthetic Bone Substitute in the Anterior Zone: Results After 12 Months. Int J Periodontics Restorative Dent. 2018 Mar/Apr;38(2):235-243. doi: 10.11607/prd.2863.